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Abstract
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Abstract
Natural compounds obtained from vegetables,
fruits or medicinal plants have been widely
used in recent years due to their therapeutic
and preventive properties of chronic diseases.
Quercetin is a type of flavonoid which was
found as plant pigment in most fruits and
vegetables. In studies, its various
pharmacological activities in hypoglycemia,
inflammation, and cancer as well as its
protective effects on cardiovascular diseases,
Type 2 Diabetes Mellitus (T2DM) and
hyperlipidemia have been shown. Quercetin
regulates blood glucose due to different
metabolic pathways including impaired
glucose tolerance in T2DM, stimulation of
insulin secretion, and improvement in the
insulin resistance. However, there is a need for
further clinical studies on diabetes mellitus. In
this review, the role of quercetin in diabetes
mellitus is discussed in the light of in vitro and
in vivo studies