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Abstract
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Abstract
BACKGROUND: Obesity has become an
important public health threat that is not
contagious but spreads the fastest and affects all
physiological functions of the body. Brown
adipose tissue, one of these strategies, is found
in infancy and is thought to disappear with
maturation in adult humans and has an
important place in energy expenditure.
METHODS: The literature search was made in
databases such as "Academic Google", "Web of
Science", "PubMed" and "Ulakbim".
RESULTS: The relative rediscovery of active
brown adipose tissue in adult humans has
sparked interest in this tissue as a new and
viable target to stimulate energy expenditure
and control body weight by promoting energy
distribution. Studies have shown that BAT
activation is increased by estradiol, berberine,
melatonin, allicin, leucine, butyrate, fish oil,
thyroid hormone and chronic exercise, and
sympathetic stimulation is provided.
DISCUSSION: Considering the current
literature on the relationship of leptin to brown
adipose tissue, the findings suggest that coldinduced BAT activation can reduce 'leptin resistance' in overweight / obese participants.
Conclusion: We anticipate that BAT will be used
as an alternative method to obesity and
metabolic surgery in the future.